The Nyquist frequency is double the sampling step. e.g. for data
      sampled at 5 angstroms the Nyquist frequency is 1/10 angstroms.
      It is important to have the sampling rate of the data high enough
      so that the image information stays sufficiently away from the
      Nyquist frequency, otherwise there is a danger that the high-
      resolution information in both of the reconstruction volumes
      may be correlated.